Eif3b polyclonal, anti-human, mouse, rat

Description: Rabbit IgG polyclonal antibody for Eukaryotic translation initiation factor 3 subunit B(EIF3B) detection. Tested with WB in Human;Mouse;Rat.Protein Name: Eukaryotic translation initiation factor 3 subunit B

Protein Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. .

Other Names: Eukaryotic translation initiation factor 3 subunit B {ECO:0000255|HAMAP-Rule:MF_03001}, eIF3b {ECO:0000255|HAMAP-Rule:MF_03001}, Eukaryotic translation initiation factor 3 subunit 9 {ECO:0000255|HAMAP-Rule:MF_03001}, Prt1 homolog, hPrt1, eIF-3-eta {ECO:0000255|HAMAP-Rule:MF_03001}, eIF3 p110 {ECO:0000255|HAMAP-Rule:MF_03001}, eIF3 p116, EIF3B {ECO:0000255|HAMAP-Rule:MF_03001}

Subcellular Localization: Cytoplasm .

Gene ID: 8662

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human eIF3B(755-775aa EDFRKYRKMAQELYMEQKNER), different from the related rat and mouse sequences by one amino acid.

Calculated MW: 92482

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.