EIF3H Polyclonal Antibody

Background:
Eukaryotic translation initiation factor 3 subunit His aproteinthat in humans is encoded by theEIF3Hgene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
EIF3H, EIF3S3, eIF3-gamma, eIF3-p40

Immunogen: Recombinant fusion protein of human EIF3H (NP_003747.1).

Swissprot: O15372
Gene ID: 8667

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.