EIF3L polyclonal (N-term), anti-human

Background:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Other Names:
Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011}, eIF3l {ECO:0000255|HAMAP-Rule:MF_03011}, Eukaryotic translation initiation factor 3 subunit 6-interacting protein {ECO:0000255|HAMAP-Rule:MF_03011}, Eukaryotic translation initiation factor 3 subunit E-interacting protein {ECO:0000255|HAMAP-Rule:MF_03011}, EIF3L {ECO:0000255|HAMAP-Rule:MF_03011}

Target/Specificity:
This EIF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human EIF3L.

Antigen Region:
12-40

Antigen Type: Synthetic Peptide

Gene Name: EIF3L {ECO:0000255|HAMAP-Rule:MF_03011}
Gene ID: 51386
Primary Accession: Q9Y262
NCBI Accession: NP_001229852.1;NP_057175.1
Other Accession: Q8AVJ0; Q8QZY1; Q5F428; Q3ZCK1; NP_057175.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.