EIF3S1 Antibody (C-term) Blocking Peptide

Background:
Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 [PubMed 14688252]; Fraser et al., 2007 [PubMed 17588516]).[supplied by OMIM]

Other Names:
Eukaryotic translation initiation factor 3 subunit J {ECO:0000255|HAMAP-Rule:MF_03009}, eIF3j {ECO:0000255|HAMAP-Rule:MF_03009}, Eukaryotic translation initiation factor 3 subunit 1 {ECO:0000255|HAMAP-Rule:MF_03009}, eIF-3-alpha {ECO:0000255|HAMAP-Rule:MF_03009}, eIF3 p35 {ECO:0000255|HAMAP-Rule:MF_03009}, EIF3J {ECO:0000255|HAMAP-Rule:MF_03009}

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7261b was selected from the C-term region of human EIF3S1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: EIF3J {ECO:0000255|HAMAP-Rule:MF_03009}

Gene ID: 8669
Primary Accession: O75822
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.