eIF4A1 (clone M8), anti-human, mouse, rat

Background:
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.

Synonyms: DDX2A, EIF-4A, eIF-4A-I, EIF4A, eIF4A-I

Cellular Location: Cytosol

Immunogen:
Synthetic Peptide

Gene Symbol: eIF4A1

Gene ID: 1973

Swiss prot: P60842

Calculated MW: 48kDa

Recommended dilution:
WB 1:1000-3000, IF 1:100-200, IHC 1:100-200,

Purity:
Saturated ammonium sulfate precipitation

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.