EIF4A2 Polyclonal Antibody

Background:
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ATP dependent RNA helicase eIF4A 2, ATP-dependent RNA helicase eIF4A-2, BM-010, DDX2B, eIF 4A II, eIF-4A-II, EIF4A, eIF4A II, eIF4A-II, EIF4A2, EIF4F, Eukaryotic initiation factor 4A II, Eukaryotic initiation factor 4A-II, eukaryotic translation initiation factor 4A isoform 2, Eukaryotic translation initiation factor 4A2, IF4A2, N-terminally processed

Immunogen: Fusion protein of human EIF4A2

Swissprot: Q14240
Gene Accession: BC016295

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.