EIF4A2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP9190B
Catalog Number: AC-AP9190B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23766
Applications: WB, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23766
Applications: WB, FC, IHC-P
Datasheet
Request Information
Background:
Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).
Other Names:
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2, EIF4A2, DDX2B, EIF4F
Target/Specificity:
This EIF4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-360 amino acids from the C-terminal region of human EIF4A2.
Antigen Region:
333-360
Antigen Type: Synthetic Peptide
Gene Name: EIF4A2
Gene ID: 1974
Primary Accession: Q14240
NCBI Accession: NP_001958.2
Other Accession: Q5RKI1; P10630; Q4R4Y9; Q8JFP1; Q3SZ65; P29562; P60843; Q4R8K5; P60842; Q3SZ54
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).
Other Names:
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2, EIF4A2, DDX2B, EIF4F
Target/Specificity:
This EIF4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-360 amino acids from the C-terminal region of human EIF4A2.
Antigen Region:
333-360
Antigen Type: Synthetic Peptide
Gene Name: EIF4A2
Gene ID: 1974
Primary Accession: Q14240
NCBI Accession: NP_001958.2
Other Accession: Q5RKI1; P10630; Q4R4Y9; Q8JFP1; Q3SZ65; P29562; P60843; Q4R8K5; P60842; Q3SZ54
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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