EIF4EBP1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Synonyms: 4E-BP1, 4EBP1, BP-1, PHAS-I

Cellular Location: Cytosol

Immunogen:
A synthetic peptide of human EIF4EBP1

Gene Symbol: EIF4EBP1

Gene ID: 1978

Swiss prot: Q13541

Calculated MW: 13kDa

Recommended dilution:
WB 1:500-1000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.