EIF4EBP1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP12627c
Catalog Number: AC-AP12627c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB11691
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB11691
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq].
Other Names:
Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Target/Specificity:
This EIF4EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the Central region of human EIF4EBP1.
Antigen Region:
31-61
Antigen Type: Synthetic Peptide
Gene Name: EIF4EBP1
Gene ID: 1978
Primary Accession: Q13541
NCBI Accession: NP_004086.1
Other Accession: Q62622; Q60876; Q0P5A7; NP_004086.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq].
Other Names:
Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Target/Specificity:
This EIF4EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the Central region of human EIF4EBP1.
Antigen Region:
31-61
Antigen Type: Synthetic Peptide
Gene Name: EIF4EBP1
Gene ID: 1978
Primary Accession: Q13541
NCBI Accession: NP_004086.1
Other Accession: Q62622; Q60876; Q0P5A7; NP_004086.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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