EIF4EBP2 Polyclonal Antibody

Background:
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Research Area: Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
4E-BP2, 4EBP2, 4EBP2, eIF4E binding protein 2, eIF4E-binding protein 2, Eif4ebp2, Eukaryotic translation initiation factor 4E binding protein 1, Eukaryotic translation initiation factor 4E-binding protein 2, PHASII, phosphorylated, heat and acid stable regulated by insulin protein II

Immunogen: Recombinant protein of human EIF4EBP2

Swissprot: Q13542
Gene Accession: BC005057

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.