EIF4G1 antibody (clone 2A9), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT1881a
Catalog Number: AC-AT1881a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT1881a-EIF4G1-Antibody-monoclonal-M10">Request Information AC-AT1881a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT1881a-EIF4G1-Antibody-monoclonal-M10">Request Information AC-AT1881a">Request Information
Background:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Other Names:
Eukaryotic translation initiation factor 4 gamma 1, eIF-4-gamma 1, eIF-4G 1, eIF-4G1, p220, EIF4G1, EIF4F, EIF4G, EIF4GI
Antigen Type:
Recombinant Protein
Gene Name: EIF4G1
Gene ID: 1981
NCBI Accession: NP_004944.3;NP_886553.3;NP_937884.1;NP_937885.1
Primary Accession: Q04637
Other Accession: NM_182917
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Other Names:
Eukaryotic translation initiation factor 4 gamma 1, eIF-4-gamma 1, eIF-4G 1, eIF-4G1, p220, EIF4G1, EIF4F, EIF4G, EIF4GI
Antigen Type:
Recombinant Protein
Gene Name: EIF4G1
Gene ID: 1981
NCBI Accession: NP_004944.3;NP_886553.3;NP_937884.1;NP_937885.1
Primary Accession: Q04637
Other Accession: NM_182917
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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