EIF4G2 antibody (clone 3B5), anti-human, rat
€435.00
In stock
SKU
AC-AT1882a
Catalog Number: AC-AT1882a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHChttps://www.abcepta.com/products/pdf_download/AT1882a-EIF4G2-Antibody-monoclonal-M01">Request Information AC-AT1882a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHChttps://www.abcepta.com/products/pdf_download/AT1882a-EIF4G2-Antibody-monoclonal-M01">Request Information AC-AT1882a">Request Information
Background:
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Other Names:
Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97, EIF4G2 (HGNC:3297)
Antigen Type:
Recombinant Protein
Gene Name: EIF4G2 (HGNC:3297)
Gene ID: 1982
NCBI Accession: NP_001036024.3;NP_001166176.1;NP_001409.3
Primary Accession: P78344
Other Accession: NM_001418
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Other Names:
Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97, EIF4G2 (HGNC:3297)
Antigen Type:
Recombinant Protein
Gene Name: EIF4G2 (HGNC:3297)
Gene ID: 1982
NCBI Accession: NP_001036024.3;NP_001166176.1;NP_001409.3
Primary Accession: P78344
Other Accession: NM_001418
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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