ELAC2 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: ELC2, HPC2, COXPD17

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human ELAC2

Gene Symbol: ELAC2

Gene ID: 60528

Swiss prot: Q9BQ52

Calculated MW: 92kDa

Recommended dilution:
WB 1:200-1000, IHC 1:20-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.