ELAVL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6592
Background:
The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts.
Alternative Name:
ELAV-like protein 1, Hu-antigen R, HuR, ELAVL1, HUR
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: ELAVL1 polyclonal antibody detects endogenous levels of ELAVL1 protein.
Immunogen:
Recombinant full length Human ELAVL1.
MW: ~ 36 kDa
Swis Prot.: Q15717
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts.
Alternative Name:
ELAV-like protein 1, Hu-antigen R, HuR, ELAVL1, HUR
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: ELAVL1 polyclonal antibody detects endogenous levels of ELAVL1 protein.
Immunogen:
Recombinant full length Human ELAVL1.
MW: ~ 36 kDa
Swis Prot.: Q15717
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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