ELAVL1 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ELAV (embryonic lethal abnormal vision Drosophila) like 1, ELAV (embryonic lethal, abnormal vision, Drosophila) like 1 (Hu antigen R), ELAV like 1, ELAV like RNA binding protein 1, ELAV-like protein 1, ELAV1, ELAV1, Elavl1, Embryonic lethal abnormal vision drosophila homolog like 1, Hu Antigen R, Hu-antigen R, Hua, HuR, MelG

Immunogen: Recombinant protein of human ELAVL1

Swissprot: Q15717
Gene Accession: BC003376

Calculated MW: 36 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5483/sc-20694