ELAVL3 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13333a
Background:
A member of the ELAVL protein family, ELAV-like 3 is aneural-specific RNA-binding protein which contains three RNP-typeRNA recognition motifs. The observation that ELAVL3 is one ofseveral Hu antigens (neuronal-specific RNA-binding proteins)recognized by the anti-Hu serum antibody present in sera frompatients with paraneoplastic encephalomyelitis and sensoryneuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Twoalternatively spliced transcript variants encoding distinctisoforms have been found for this gene.
Other Names:
ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13333a was selected from the N-term region of ELAVL3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ELAVL3
Gene ID: 1995
Primary Accession: Q14576
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
A member of the ELAVL protein family, ELAV-like 3 is aneural-specific RNA-binding protein which contains three RNP-typeRNA recognition motifs. The observation that ELAVL3 is one ofseveral Hu antigens (neuronal-specific RNA-binding proteins)recognized by the anti-Hu serum antibody present in sera frompatients with paraneoplastic encephalomyelitis and sensoryneuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Twoalternatively spliced transcript variants encoding distinctisoforms have been found for this gene.
Other Names:
ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13333a was selected from the N-term region of ELAVL3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ELAVL3
Gene ID: 1995
Primary Accession: Q14576
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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