ELAVL3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70716
Background:
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
HUC, HUCL, PLE21, ELAV-like protein 3, Hu-antigen C
Application Dilution: WB: 1:500 - 1:1000, IHC: 1:50 - 1:200
Specificity: ELAVL3 polyclonal antibody detects endogenous levels of ELAVL3 protein.
Immunogen:
A synthetic peptide of human ELAVL3.
MW: ~ 39 kDa
Swis Prot.: Q14576
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
HUC, HUCL, PLE21, ELAV-like protein 3, Hu-antigen C
Application Dilution: WB: 1:500 - 1:1000, IHC: 1:50 - 1:200
Specificity: ELAVL3 polyclonal antibody detects endogenous levels of ELAVL3 protein.
Immunogen:
A synthetic peptide of human ELAVL3.
MW: ~ 39 kDa
Swis Prot.: Q14576
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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