ELOVL1 Polyclonal Antibody

Background:
Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

Research Area: Cardiovascular, Metabolism, Signal Transduction

Synonyms:
3 keto acyl CoA synthase ELOVL1, 3-keto acyl-CoA synthase ELOVL1, CGI 88, Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1, Elongation of very long chain fatty acids like 1, Elongation of very long chain fatty acids protein 1, ELOV1, ELOVL 1, ELOVL FA elongase 1, ELOVL fatty acid elongase 1, ELOVL1, Ssc1, Ssc1, mouse, homolog of, very long chain 3 oxoacyl CoA synthase 1, Very-long-chain 3-oxoacyl-CoA synthase 1

Immunogen: Recombinant protein of human ELOVL1

Swissprot: Q9BW60
Gene Accession: BC000618

Calculated MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-54870/sc-135058