ELP3 Antibody (N-term) Blocking Peptide

Background:
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.

Other Names:
Elongator complex protein 3, hELP3, ELP3

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1112a was selected from the N-term region of human ELP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: ELP3 {ECO:0000303|PubMed:15902492, ECO:0000312|HGNC:HGNC:20696}

Gene ID: 55140
Primary Accession: Q9H9T3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.