EMC8 Polyclonal Antibody

Background:
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Area: Cell Biology

Synonyms:
C16orf2, C16orf4, COX4 neighbor, COX4, neighbor of, COX4AL, Cox4nb, CX4NB, ER membrane protein complex subunit 8, FAM158B, family with sequence similarity 158, member B, Neighbor of COX4, NOC4, Protein FAM158B

Immunogen: Recombinant protein of human EMC8

Swissprot: O43402
Gene Accession: BC001472

Calculated MW: 24 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-107509/sc-98311