EML4 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS72843
Background:
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Alternative Name:
C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120
Application Dilution: WB: 1:500 - 1:2000
Specificity: EML4 polyclonal antibody detects endogenous levels of EML4 protein.
Immunogen:
Recombinant protein of human EML4
MW: Refer to figures
Swis Prot.: Q9HC35
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Alternative Name:
C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120
Application Dilution: WB: 1:500 - 1:2000
Specificity: EML4 polyclonal antibody detects endogenous levels of EML4 protein.
Immunogen:
Recombinant protein of human EML4
MW: Refer to figures
Swis Prot.: Q9HC35
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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