EN1 (Engrailed 1) Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP7278c
Background:
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Other Names:
Homeobox protein engrailed-1, Homeobox protein en-1, Hu-En-1, EN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7278c was selected from the Center region of human EN1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: EN1
Gene ID: 2019
Primary Accession: Q05925
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Other Names:
Homeobox protein engrailed-1, Homeobox protein en-1, Hu-En-1, EN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7278c was selected from the Center region of human EN1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: EN1
Gene ID: 2019
Primary Accession: Q05925
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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