EN2 Polyclonal Antibody

Background:
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Stem cells

Synonyms:
AUTS 1, AUTS1, EN 2, Engrailed 2, Engrailed homeo box 2, Engrailed homeobox 2, Engrailed homolog 2, Engrailed2, Homeobox protein engrailed 2, Homeobox protein engrailed2, Hu En 2 , HuEn2, MabEn

Immunogen: Synthetic peptide of human EN2

Swissprot: P19622
Gene Accession: NP001418

Calculated MW: 34 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.