ENaC beta (Phospho Thr615) polyclonal antibody, anti-human, mouse, rat

Background:
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

Research Area: Cancer, Metabolism, Neuroscience, Signal transduction

Synonyms: Amiloride-sensitive sodium channel subunit beta, SCNN1B, Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na, + channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year