Endomucin polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
Endomucin is a protein that in humans is encoded by the EMCN gene. It is mapped to 4q24. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. Using suppression subtractive hybridization (SSH), people found endomucin a potential cell surface marker upregulated. Human endomucin is predicted to encode a 261-aa, 27.5-kDa protein with a transmembrane sequence and multiple glycosylation sites. Northern and in situ hybridization studies show that human endomucin expression is largely, if not uniquely, endothelial cell-specific. And human endomucin is present abundantly in highly vascular tissues such as heart, kidney, and lung.

Description:
Rabbit IgG polyclonal antibody for Endomucin (EMCN) detection. Tested with WB in Human, Mouse.

Synonyms:
EMCN antibody, EMCN2 antibody, Endomucin 2 antibody, Endomucin antibody, Endomucin-2 antibody, Endothelial sialomucin antibody, Gastric cancer antigen Ga34 antibody, MUC-14 antibody, MUC14 antibody, MUCEN_HUMAN antibody, Mucin 14 antibody, Mucin-14 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Endomucin (225-258aa ENGNDQPQSDKESVKLLTVKTISHESGEHSAQGK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.