ENG polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11239c
Catalog Number: AC-AP11239c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20948
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20948
Applications: FC, WB
Datasheet
Request Information
Background:
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Endoglin, CD105, ENG, END
Target/Specificity:
This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG.
Antigen Region:
265-294
Antigen Type: Synthetic Peptide
Gene Name: ENG
Gene ID: 2022
Primary Accession: P17813
NCBI Accession: NP_000109.1;NP_001108225.1;NP_001265067.1
Other Accession: NP_001108225.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Endoglin, CD105, ENG, END
Target/Specificity:
This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG.
Antigen Region:
265-294
Antigen Type: Synthetic Peptide
Gene Name: ENG
Gene ID: 2022
Primary Accession: P17813
NCBI Accession: NP_000109.1;NP_001108225.1;NP_001265067.1
Other Accession: NP_001108225.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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