ENO1 Polyclonal Antibody

Background:
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
ENO1, ENO1L1, HEL-S-17, MPB1, NNE, PPH, enolase 1

Immunogen: Recombinant fusion protein of human ENO1 (NP_001419.1).

Swissprot: P06733
Gene ID: 2023

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.