FADD polyclonal, anti-human
€470.00
In stock
SKU
AC-AP51203
Background:
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Other Names:
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1
Antigen Type: synthetic peptide
Antigen Type: FADD {ECO:0000303|PubMed:7538907, ECO:0000312|HGNC:HGNC:3573}
Gene ID: 8772
Primary Accession: Q13158
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Other Names:
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1
Antigen Type: synthetic peptide
Antigen Type: FADD {ECO:0000303|PubMed:7538907, ECO:0000312|HGNC:HGNC:3573}
Gene ID: 8772
Primary Accession: Q13158
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