eNOS (clone 6H2), anti-human
€478.00
In stock
SKU
252928
Protein Family: Enzymes
Pathway and Disease: Amino Acid Metabolism, Signal Transduction, Signaling Molecules and Interaction
Description:
eNOS (Endothelial NOS) is a nitric oxyde synthase enzyme, part of the Nitric oxyde pathway. Nitric oxide synthases (NOS) are enzymes that catalyze the generation of nitric oxide (NO) from L-arginine and require nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. At least three isioforms of NOS have been idenified: neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS). NOS-3 (eNOS, endothelial NOS) produces NO which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Alternate Names: NOS-3, eNOS, Endothelial NOS, Nitric oxide synthase, endothelial, EC-NOS, NOS type III, NOSIII, Constitutive NOS, cNOS, NOS3
Application Notes: E: 1:1000-1:10000; IHC: 1:200-1:1000
Accession No.: P29474
Antigen: Purified recombinant fragment of human eNOS expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Amino Acid Metabolism, Signal Transduction, Signaling Molecules and Interaction
Description:
eNOS (Endothelial NOS) is a nitric oxyde synthase enzyme, part of the Nitric oxyde pathway. Nitric oxide synthases (NOS) are enzymes that catalyze the generation of nitric oxide (NO) from L-arginine and require nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. At least three isioforms of NOS have been idenified: neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS). NOS-3 (eNOS, endothelial NOS) produces NO which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Alternate Names: NOS-3, eNOS, Endothelial NOS, Nitric oxide synthase, endothelial, EC-NOS, NOS type III, NOSIII, Constitutive NOS, cNOS, NOS3
Application Notes: E: 1:1000-1:10000; IHC: 1:200-1:1000
Accession No.: P29474
Antigen: Purified recombinant fragment of human eNOS expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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