ENT1 polyclonal (C-term), anti-human, mouse

ENT1 polyclonal (C-term), anti-human, mouse

€0.00
In stock
SKU
AC-AP1086b
Catalog Number: AC-AP1086b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB09157
Applications: WB, FC, IHC-P-Leica
Datasheet

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Background:
ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.

Other Names:
Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1

Target/Specificity:
This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human ENT1.

Antigen Region:
402-431

Antigen Type: Synthetic Peptide

Gene Name: SLC29A1 (HGNC:11003)
Gene ID: 2030
Primary Accession: Q99808
NCBI Accession: NP_001071642.1;NP_001071643.1;NP_001071644.1;NP_001071645.1;NP_004946.1
Other Accession: O54698; Q9JIM1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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