DNA Ligase III polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP69548
Catalog Number: AC-AP51453
Size: 100 µl
Host: Rabbit
Applications: WB, IP, IHC-P, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IP, IHC-P, E
Datasheet
Request Information
Background:
Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand- break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).
Other Names:
LIG3; DNA ligase 3; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3
Antigen Type: synthetic peptide
Antigen Type: LIG3
Gene ID: 3980
Primary Accession: P49916
Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand- break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).
Other Names:
LIG3; DNA ligase 3; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3
Antigen Type: synthetic peptide
Antigen Type: LIG3
Gene ID: 3980
Primary Accession: P49916
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