Eotaxin polyclonal, anti-mouse

Quantity: 100 µg

Background:
CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3(CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11 is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.

Description:
Rabbit IgG polyclonal antibody for Eotaxin (CCL11) detection. Tested with WB in Mouse.

Synonyms:
C-C motif chemokine 11 antibody, CCL 11 antibody, CCL11 antibody, CCL11_HUMAN antibody, chemokine (C-C motif) ligand 11 antibody, Chemokine C C motif ligand 11 antibody, Chemokine CC Motif Ligand 11 antibody, Chemokine ligand 11 antibody, Eosinophil chemotactic protein antibody, Eotaxin antibody, eotaxin-1 antibody, MGC22554 antibody, SCYA 11 antibody, SCYA11 antibody, Small inducible cytokine A11 antibody, Small inducible cytokine subfamily A (Cys Cys) member 11 antibody, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody, Small inducible cytokine subfamily A member 11 antibody, Small-inducible cytokine A11 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse Eotaxin recombinant protein (Position: H24-P97). Mouse Eotaxin shares 62% and 97% amino acid (aa) sequences identity with human and rat Eotaxin, respectively.E.coli-derived mouse Eotaxin recombinant protein (Position: H24-P97). Mouse Eotaxin shares 62% and 97% amino acid (aa) sequences identity with human and rat Eotaxin, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.