EphA2/3/4 (phospho Tyr588/596) Polyclonal Antibody

Background:
EPH receptor A2(EPHA2) Homo sapiens This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],

Alternative Names:
EPHA2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human emb

Immunogen: The antiserum was produced against synthesized peptide derived from human EPHA2/3 around the phosphorylation site of Tyr588/596. AA range:556-605

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 130

GeneID: EPHA2/3/4

Storage: -20°C/1 year

NOTE: For Research Use Only