EPHA2 polyclonal, anti-human, mouse, rat

Background:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

Synonyms: ARCC2, CTPA, CTPP1, CTRCT6, ECK

Cellular Location: Cell junction Cell membrane Cell projection Single-pass type I membrane protein focal adhesion lamellipodium membrane ruffle membrane

Immunogen:
Recombinant protein of human EPHA2

Gene Symbol: EPHA2

Gene ID: 1969

Swiss prot: P29317

Calculated MW: 108kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.