EPHA3 Polyclonal Antibody

Background:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Research Area: Cardiovascular, Neuroscience, Signal Transduction

Synonyms:
AW492086, Cek4, EC 2.7.10.1, EK4, End3, Eph receptor A3, EPH-like kinase 4, EPH-like tyrosine kinase 1, EPHA3, EPHA3, Ephrin receptor EphA3, Ephrin type-A receptor 3, ETK 1, ETK, ETK1, HEK 4, HEK, HEK4, Human embryo kinase 1, Human embryo kinase, Mek4, MGC109882, Receptor tyrosine kinase HEK, Testicular tissue protein Li 64, Tyro 4, Tyro4, TYRO4 protein tyrosine kinase, Tyrosine protein kinase receptor ETK 1, Tyrosine-protein kinase receptor ETK1, Tyrosine-protein kinase TYRO4

Immunogen: Synthetic peptide of human EPHA3

Swissprot: P29320
Gene Accession: NP005224

Calculated MW: 110 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:2000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.