EphA8 (clone 9A12D8), anti-human
€478.00
In stock
SKU
252817
Protein Family: Enzymes, Protein Kinases, Receptors and Channels
Pathway and Disease: Cancers, Signaling Molecules and Interaction
Description:
EphA8 (EPH receptor A8) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA8 is a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
Alternate Names: Ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH-like kinase 3, EK3, hEK3, Tyrosine-protein kinase receptor EEK, EEK, HEK3, KIAA1459, EPHA8
Application Notes: WB: 1:500-1:2000
Accession No.: P29322
Antigen: Purified recombinant fragment of EphA8(aa70-150) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Signaling Molecules and Interaction
Description:
EphA8 (EPH receptor A8) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA8 is a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
Alternate Names: Ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH-like kinase 3, EK3, hEK3, Tyrosine-protein kinase receptor EEK, EEK, HEK3, KIAA1459, EPHA8
Application Notes: WB: 1:500-1:2000
Accession No.: P29322
Antigen: Purified recombinant fragment of EphA8(aa70-150) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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