EphB (Tyr331) polyclonal, anti-human, mouse, bovine, chicken, Xenopus, zebrafish
€536.00
In stock
SKU
252539
Protein Family: Cytokines
Pathway and Disease: Signal Transduction
Description:
Ephrin ligands, which bind ephrin receptors, play a role in cell migration and neural crest development. Binding of ephrin ligands to the ephrin B receptor blocks the dorsolateral migration of early-migrating neural crest cells. Conversely, ephrin B receptor signaling stimulates the dorsolateral migration of melanocytes. Collectively, research has shown that ephrin ligands are involved in the appropriate trafficking of migrating cells during neuronal development. Phosphorylation of Tyr331 plays a key role in EphrinB signaling.
Alternate Names: Ephrin-B1, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, XlERK
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: O13097
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Tyr331 of chicken EphrinB.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signal Transduction
Description:
Ephrin ligands, which bind ephrin receptors, play a role in cell migration and neural crest development. Binding of ephrin ligands to the ephrin B receptor blocks the dorsolateral migration of early-migrating neural crest cells. Conversely, ephrin B receptor signaling stimulates the dorsolateral migration of melanocytes. Collectively, research has shown that ephrin ligands are involved in the appropriate trafficking of migrating cells during neuronal development. Phosphorylation of Tyr331 plays a key role in EphrinB signaling.
Alternate Names: Ephrin-B1, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, XlERK
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: O13097
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Tyr331 of chicken EphrinB.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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