EphB1/2/3/4 (Y594) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS3742
Background:
Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
Alternative Name:
EphB1, EphB2, EphB3, EphB4,
Application Dilution: IHC: 1:50~1:200
Specificity: EphB1/2/3/4 (Y594) polyclonal antibody detects endogenous levels of EphB1/2/3/4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.
MW: ~ 118 kDa
Swis Prot.: P54762/P29323/P54753/P54760
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
Alternative Name:
EphB1, EphB2, EphB3, EphB4,
Application Dilution: IHC: 1:50~1:200
Specificity: EphB1/2/3/4 (Y594) polyclonal antibody detects endogenous levels of EphB1/2/3/4 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.
MW: ~ 118 kDa
Swis Prot.: P54762/P29323/P54753/P54760
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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