EPHB3 (Phospho Tyr608) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
Ephrin receptors and their ligands| the ephrins| mediate numerous developmental processes| particularly in the nervous system. Based on their structures and sequence relationships| ephrins are divided into the ephrin-A (EFNA) class| which are anchored to the membrane by a glycosylphosphatidylinositol linkage| and the ephrin-B (EFNB) class| which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

Research Area: Neuroscience

Synonyms: EPHB3 , Phospho Tyr608, Ephrin type-B receptor 3, EC 2.7.10.1, EPH-like tyrosine kinase 2, EPH-like kinase 2, Embryonic kinase 2, EK2, hEK2, Tyrosine-protein kinase TYRO6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year