EphB3 polyclonal, anti-human, mouse

EphB3 polyclonal, anti-human, mouse

€0.00
In stock
SKU
AC-AP7624d
Catalog Number: AC-AP7624d
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16728
Applications: FC, WB
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Background:
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family; it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).

Other Names:
Ephrin type-B receptor 3, EPH-like tyrosine kinase 2, EPH-like kinase 2, Embryonic kinase 2, EK2, hEK2, Tyrosine-protein kinase TYRO6, EPHB3, ETK2, HEK2, TYRO6

Target/Specificity:
This EphB3 antibody is generated from rabbits immunized with EphB3 his fusion protein.

Antigen Type: Recombinant Protein

Gene Name: EPHB3
Gene ID: 2049
Primary Accession: P54753
NCBI Accession: NP_004434.2
Other Accession: NP_004434
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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