EPHB3 Polyclonal Antibody

Background:
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

Research Area: Cancer, Neuroscience

Synonyms:
Cek10, EK2, Embryonic kinase 2, EPH Like Tyrosine Kinase 2, EPH receptor B3, EPH-like kinase 2, ephb3, EPHB3, Ephrin receptor EphB3, Ephrin type B receptor 3, Ephrin type-B receptor 3, ETK2, hEK2, Human Embryo Kinase 2, Mdk5, Sek4, TYRO6, Tyrosine protein kinase receptor HEK2, Tyrosine protein kinase TYRO6, Tyrosine-protein kinase TYRO6

Immunogen: Synthetic peptide of human EPHB3

Swissprot: P54753
Gene Accession: NP_004434

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9318/sc-27111/sc-27110/sc-28981