EPHB4 Polyclonal Antibody

Background:
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Research Area: Cardiovascular, Neuroscience, Stem Cells

Synonyms:
EPHB4, HFASD, HTK, MYK1, TYRO11

Immunogen: Recombinant fusion protein of human EPHB4 (NP_004435.3).

Swissprot: P54760
Gene ID: 2050

Calculated MW: 108 kDa
Observed MW: 108 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:200-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.