EphB6 polyclonal (N-term S45), anti-human

EphB6 polyclonal (N-term S45), anti-human

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In stock
SKU
AC-AP7627A
Catalog Number: AC-AP7627A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1663
Applications: WB, FC, IHC-P
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Background:
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Other Names:
Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6

Target/Specificity:
This EphB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human EphB6.

Antigen Region:
45-74

Antigen Type: Synthetic Peptide

Gene Name: EPHB6
Gene ID: 2051
Primary Accession: O15197
NCBI Accession: NP_001267723.1;NP_001267724.1;NP_004436.3
Other Accession: P0C0K7; O08644
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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