Ephrin A5 Polyclonal Antibody

Background:
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997).

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
EPLG7, AF1, AL 1, AL-1, EFL5, Efna5, EFNA5, EPH-related receptor tyrosine kinase ligand 7, Ephrin A5, Ephrin-A5, EPLG7, GLC1M, LERK-7, LERK7, RAGS

Immunogen: Synthetic peptide of human EFNA5

Swissprot: P52803
Gene Accession: NP_001953

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1951/sc-6075/sc-20722