Ephrin-A5 Polyclonal Antibody

Background:
ephrin A5(EFNA5) Homo sapiens Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divi

Alternative Names:
EFNA5, EPLG7, LERK7, Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7

Immunogen: Synthesized peptide derived from Ephrin-A5 . at AA range: 130-210

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 26

GeneID: EFNA5

Storage: -20°C/1 year

NOTE: For Research Use Only