EPO Receptor Picoband polyclonal, anti-mouse, rat
€455.00
In stock
SKU
AC-ABO12839
Catalog Number: AC-ABO12839
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for EPO Receptor detection. Tested with WB, Direct ELISA in Mouse;Rat.
Protein Function:
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Other Names: Erythropoietin receptor, EPO-R, Epor
Subcellular Localization: Isoform EPOR-F: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells.
Gene ID: 13857
Immunogen: E. coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225).
Calculated MW: 55194
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
Protein Function:
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Other Names: Erythropoietin receptor, EPO-R, Epor
Subcellular Localization: Isoform EPOR-F: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells.
Gene ID: 13857
Immunogen: E. coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225).
Calculated MW: 55194
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
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