EPOR antibody (clone 3D10), anti-human
€435.00
In stock
SKU
AC-AT1931a
Catalog Number: AC-AT1931a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IP, E
Request Information AC-AT1931a">Request Information
Background:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Other Names:
Erythropoietin receptor, EPO-R, EPOR
Antigen Type:
Recombinant Protein
Gene Name: EPOR {ECO:0000303|PubMed:2163695, ECO:0000312|HGNC:HGNC:3416}
Gene ID: 2057
NCBI Accession: NP_000112.1
Primary Accession: P19235
Other Accession: NM_000121
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Other Names:
Erythropoietin receptor, EPO-R, EPOR
Antigen Type:
Recombinant Protein
Gene Name: EPOR {ECO:0000303|PubMed:2163695, ECO:0000312|HGNC:HGNC:3416}
Gene ID: 2057
NCBI Accession: NP_000112.1
Primary Accession: P19235
Other Accession: NM_000121
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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