EPOR polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP16681c
Catalog Number: AC-AP16681c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30358
Applications: IF, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30358
Applications: IF, FC, WB
Datasheet
Request Information
Background:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Other Names:
Erythropoietin receptor, EPO-R, EPOR
Target/Specificity:
This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.
Antigen Region:
329-357
Antigen Type: Synthetic Peptide
Gene Name: EPOR {ECO:0000303|PubMed:2163695, ECO:0000312|HGNC:HGNC:3416}
Gene ID: 2057
Primary Accession: P19235
NCBI Accession: NP_000112.1
Other Accession: NP_000112.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Other Names:
Erythropoietin receptor, EPO-R, EPOR
Target/Specificity:
This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.
Antigen Region:
329-357
Antigen Type: Synthetic Peptide
Gene Name: EPOR {ECO:0000303|PubMed:2163695, ECO:0000312|HGNC:HGNC:3416}
Gene ID: 2057
Primary Accession: P19235
NCBI Accession: NP_000112.1
Other Accession: NP_000112.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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