EPS15L1 Polyclonal Antibody

Background:
Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Research Area: Cancer, Signal Transduction

Synonyms:
EP15R, epidermal growth factor receptor pathway substrate 15- ike 1, Epidermal growth factor receptor substrate 15 like 1, Epidermal growth factor receptor substrate 15-like 1, epidermal growth factor receptor substrate EPS15R, Eps15 related protein, Eps15-related protein, EPS15L1, Eps15R

Immunogen: Recombinant protein of human EPS15L1

Swissprot: Q9UBC2
Gene Accession: BC131590

Calculated MW: 94 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-130138