ERAL1 Polyclonal Antibody

Background:
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Signal Transduction

Synonyms:
CEGA, Conserved ERA like GTPase, Conserved ERA-like GTPase, ERA, Era (E.coli G protein homolog) like 1, Era G protein like 1 (E.coli), Era G protein like 1, ERA W, ERA-like protein 1, ERA-W, Eral1, ERAL1, ERAL1A, ERAW, GTP binding protein era homolog, GTPase Era, GTPase Era, mitochondrial, GTPase human homolog of E.coli essential cell cycle protein Era, H-ERA, HERA A, hERA, HERA B, HERAA, HERAB, mitochondrial

Immunogen: Recombinant Human GTPase Era, mitochondrial protein

Swissprot: O75616

Calculated MW: 47 kDa
Observed MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.